The season began on 17 October 2010 with the Volta de São Paulo and ended on 17 September 2011 with the Univest Grand Prix.

The points leader, based on the cumulative results of previous races, wears the UCI America Tour cycling jersey.

Gregorio Ladino of Colombia was the defending champion of the 2009–10 UCI America Tour.

Miguel Ubeto of Venezuela was crowned as the 2010–11 UCI America Tour champion.

The quality and complexity of a race also determines how many points are awarded to the top finishers, the higher the UCI rating of a race, the more points are awarded.