This article details the 2010–11 UEFA Europa League play-off round.
The team that had the higher aggregate score over the two legs qualified for the next round.
In the event that aggregate scores finished level, the away goals rule was applied; i.e. the team that scored more goals away from home over the two legs progressed.
If away goals were also equal, then 30 minutes of extra time was played, divided into two 15-minute halves.
If no goals were scored during extra time, the tie was decided by a penalty shootout.
All draws were held at UEFA headquarters in Nyon, Switzerland.
[1] Matches may also be played on Tuesdays or Wednesdays instead of the regular Thursdays due to scheduling conflicts.
CSKA Moscow Bayer Leverkusen Paris Saint-Germain Unirea Urziceni Feyenoord Anorthosis Famagusta Tavriya Simferopol Gent Maccabi Tel Aviv Hajduk Split Porto Galatasaray Palermo Austria Wien Litex Lovech Aris Genk Karpaty Lviv Debrecen Maribor Sporting CP Lille Club Brugge Metalist Kharkiv Napoli Brøndby Vaslui IF Elfsborg Omonia Dinamo Minsk Liverpool Steaua București Celtic Levski Sofia Borussia Dortmund Grasshopper Trabzonspor Utrecht
Lech Poznań Sturm Graz Dundee United Aktobe PSV Eindhoven VfB Stuttgart Beşiktaş Aston Villa CSKA Sofia BATE Borisov Rapid Wien Sibir Novosibirsk Marítimo Slovan Bratislava
The New Saints Villarreal Fenerbahçe Manchester City Lokomotiv Moscow Odense Dinamo Zagreb Timișoara