They played their home games at the Thomas & Mack Center on UNLV's main campus in Paradise, Nevada and are a member of the Mountain West Conference.

UNLV finished the 2009–2010 season with a 25–9 record, losing to Northern Iowa in the first round of the 2010 NCAA Division I men's basketball tournament, 69–66.

[1] About a month later, it was announced that power forward Matt Shaw would be ineligible for his senior season because he tested positive for a banned substance.

[4] Four weeks later, senior guard Tre'Von Willis was suspended for at least 10% of the season due to a June 29 arrested by the Henderson Police Department.

[6] The Runnin' Rebels were picked to finish fourth in the Mountain West Conference, behind defending conference tournament champion San Diego State Aztecs, the BYU Cougars led by preseason player of the year (Jimmer Fredette) and defending regular season champion, the New Mexico Lobos.