The 2010–11 UTSA Roadrunners men's basketball team represented the University of Texas at San Antonio in the 2010–11 college basketball season.

This was head coach Brooks Thompson's fifth season at UTSA.

They played their home games at the Convocation Center.

The Roadrunners finished the season 20–14, 9–7 in Southland play to finish in third place in the West Division.

UTSA defeated Alabama State in the First Four, 70–61, before falling to top-seed Ohio State in the round of 64.