The 2010–11 EHF Women's Cup Winners' Cup was the 35th edition of the tournament that is organized by the European Handball Federation for the domestic cup winners on the continent.

ŽRK Budućnost Podgorica were the title holders, however, as Montenegrin champions they entered the EHF Champions League this season.

Ferencvárosi TC won the trophy for the second time in the club's history after beating CB Mar Alicante 57–52 on aggregate in the finals.

[1] CL Relegated from the EHF Champions League All draws held at the European Handball Federation headquarters in Vienna, Austria.