[3] The regular season started on November 5, 2010, with the expansion team St. Louis Pioneers on the road to defeat the Chicago Steam, 93–73.
Before and during the first month of the ABA regular season, league offices reported new teams starting up in Richmond, Norfolk, Flint, Little Rock, Atlanta, Lynchburg (Virginia), among others.
The Southeast Texas Mavericks, after recently extending their regular season game winning streak to twenty,[10] were later defeated on the road against the Gulf Coast Flash by two points on December 21, falling to 9–1.
[11] In late December, Marlo Saunders of the West Texas Whirlwinds surpassed 1,000 points scored and 500 rebounds in his short two-year career in the ABA, joining teammates Ray Williams and Charncy Ephriam as the only Whirlwinds to accomplish the feat.
Kayode Ayeni, a forward from the Jersey Express, was rewarded with the game's Most Valuable Player award after scoring a game-high 25 points.
The Gulf Coast Flash won the Eastern Conference title over the East Kentucky Energy, and the Mustangs beat the Giants to win the Western.