Richmond competed as a member of the Colonial Athletic Association (CAA) under first-year head football coach Latrell Scott and played its home games at the new E. Claiborne Robins Stadium.

The 2010 campaign came on the heels of an NCAA Division I FCS national championship in 2008 and a quarterfinal appearance in 2009.

In the Colonial Athletic Association preseason poll, the Spiders were picked to finish 6th in the conference.

Richmond's 2010 schedule[2] kicked off against Football Bowl Subdivision (FBS) team Virginia and includes other non-conference games against Elon and Coastal Carolina.

The schedule also included an eight-game CAA slate wrapping up against rival William & Mary in the Capital Cup.