The 2010 Sacred Heart Pioneers football team represented Sacred Heart University as a member of the Northeast Conference (NEC) during the 2010 NCAA Division I FCS football season.
Led by seventh-year head coach Paul Gorham, the Pioneers compiled an overall record of 4–7 with a mark of 2–6 in conference play, placing eighth in the NEC.
Sacred Heart played home games at Campus Field in Fairfield, Connecticut.
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