The Women's road race of the 2010 UCI Road World Championships cycling event took place on 2 October in Melbourne, Australia.

For the third time in four years, an Italian rider claimed the gold medal, with Giorgia Bronzini edging out her rivals in a sprint finish.

Dutch rider Marianne Vos finished second for her fourth consecutive silver medal in the event, with Emma Johansson of Sweden taking the bronze.

[1] The race covered 127.2 km.

[2]