The 2010 Western Kentucky Hilltoppers football team represented Western Kentucky University (WKU) in the 2010 NCAA Division I FBS football season.

The Hilltoppers were led by first-year head coach Willie Taggart and played their home games at Houchens Industries–L.

They are members of the Sun Belt Conference.

The 2 wins by the team marked the first and second victories as members of the Sun Belt.

This college football 2010s season article is a stub.