The Avalanche failed to qualify for the 2012 Stanley Cup playoffs, finishing seven points behind the eighth-placed Los Angeles Kings in the Western Conference.
On June 16, 2011, the Avalanche promoted former player Adam Deadmarsh to assistant coach.
The Avalanche retired Peter Forsberg's number 21 jersey on opening night, October 8.
Note: GP = Games played; G = Goals; A = Assists; Pts = Points; +/− = Plus/minus; PIM = Penalty minutes
Note: GP = Games played; TOI = Time on ice (minutes); W = Wins; L = Losses; OT = Overtime losses; GA = Goals against; GAA= Goals against average; SA= Shots against; Sv% = Save percentage; SO= Shutouts; G= Goals; A= Assists; PIM= Penalties in minutes †Denotes player spent time with another team before joining Avalanche.