It began on 28 August 2011 with Round 1 and ended on 26 May 2012 with the Final held at Stade Josy Barthel in Luxembourg City.
FC Differdange 03 are the defending champions, having won their second cup title last season.
Thirty-six of them competed in matches, while the other fourteen teams were awarded a bye to the next round.
Bye: Alisontia Steinsel, US Berdorf/Consdorf, Blo-Weiss Medernach, FC Brouch, AS Colmar-Berg, Jeunesse Gilsdorf, Jeunesse Sportive Koerich, Les Ardoisiers Perlé, Minière Lasauvage, Racing Troisvierges, Red Star Merl/Belair, US Reisdorf, Rupensia Lusitanos Larochette, Union Remich/Bous The eighteen winners of Round 1 and the fourteen teams that received a bye competed in this round.
The games were played on 28, 29 and 30 October and 9 November 2011.