In a change from last season, this year's competition will include all teams from Malta and Gozo.
The competition began on 8 September 2011 and will ended 27 May 2012 with the Final in Ta' Qali Stadium.
The defending champions are Floriana, having won their 19th Maltese Cup last season and first since 1994.
Floriana were the defending champions, but were eliminated in the quarter-finals by Hibernians.
The last time Qormi and Hibernians met together in Maltese FA Trophy was during the 2009-10 Quater-finals when Qormi beat Hibernians 4–3 on penalties when the match ends 1–1 draw.