The 2011–12 season in Primera División de Nicaragua will be divided into two tournaments (Apertura and Clausura) and will determine the 59th and 60th champions in the history of the league.

It will also provide the sole berth for the 2012–13 CONCACAF Champions League.

Promoted from Segunda División de Fútbol Nicaragua.

Relegated to Segunda División de Fútbol Nicaragua.

Chinandega Diriangén FC Juventus Managua Managua (player released mid season) Ocotal Real Esteli Real Madriz Walter Ferretti