San Luis began their season on July 23, 2011 against UNAM, San Luis play their homes games on Saturdays at 8:45pm local time.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

San Luis did not qualify to the Final Phase [3] Last updated: 5 November 2011.

Source: Apertura 2010 results Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

San Luis did not qualify to the Final Phase [10] Last updated: 29 April 2012.