The club will not compete in the 2012 AFC Champions League after failing to qualify during the previous season.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

†The Round 9 fixture against the Brisbane Roar was moved from the Sydney Football Stadium to Jubilee Oval due to an Eminem concert being held at the Sydney Football Stadium on the same day[58] †The Round 10, regional fixture against Perth Glory was postponed until further notice, due to the Perth squad unable to leave Perth Airport due to bad weather.

[41] Correct as of Round 14 †The Round 9 fixture against the Brisbane Roar was moved from the Sydney Football Stadium to Jubilee Oval due to an Eminem concert being held at the Sydney Football Stadium on the same day .

[58] On 26 April, 2012, Sydney FC hosted their annual Sky Blue Ball and presented six awards on the night.