UANL began their season on July 23, 2011, against Cruz Azul, UANL play their home games on Saturdays at 7:00pm local time.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Source: Apertura 2011 results Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

UANL advanced 5–1 on aggregate Santos Laguna advanced 3–3 on aggregate due to being the higher seed in the classification phase Source:[5]

Source: Clausura 2012 results Unión Española won on points 4–1.