The 2011–12 Uruguayan Segunda División is the season of second division professional of football in Uruguay.
A total of 13 teams will compete; the top two teams and the winner of the Championship play-offs are promoted to the Uruguayan Primera División.
Note: Flags indicate national team as has been defined under FIFA eligibility rules.
Huracán and Progreso qualified to the promotion playoff finals by winning their respectively matches by a single-elimination format, with each tie played over two legs.
Progreso won the match via penalties and became promoted to the 2012–13 Primera División.