Villarreal competed in La Liga and participated in the UEFA Champions League, entering in the play-off round due to their fourth-place finish in the 2010–11 La Liga.

They entered the Copa del Rey in the Round of 32.

This season would end Villarreal's streak in La Liga; on the final day of the season they lost 1–0 to Atlético Madrid, sending them down to 18th and relegating the side to the second division for the first time since the 1999–2000 season.

The numbers are established according to the official website:www.villarrealcf.es and www.lfp.es Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Source: Competitive matches Times up to 29 October 2011 (matchdays 1–3) are CEST (UTC+02:00), thereafter (matchdays 4–6) times are CET (UTC+01:00).