The Horizon League Network broadcast the opening rounds, which were played at the home courts of the higher seeds.

As Milwaukee defeated Valparaiso in its semifinal match, it secured host status for the championship game against Butler as well; the final was broadcast by ESPN/ESPN3.com.

Butler defeated Milwaukee 59–44 in the final, winning its second consecutive Horizon League tournament title and receiving an automatic bid to the 2011 NCAA tournament.

Teams were seeded by 2010–11 Horizon League season record, with a tiebreaker system to seed teams with identical conference records.

First round games at campus sites of lower-numbered seeds Second round and semifinals hosted by #1 overall seed (Milwaukee) Championship game hosted by highest remaining seed Matt Howard of Butler was named the tournament MVP for the second successive year.