The defending champions Flora won their ninth league title.
Lootus finished the 2010 season in last place and were relegated to the 2011 Esiliiga as a result, ending their one-year stay in the Estonian top flight.
Taking their place were Ajax, who finished the 2010 Esiliiga first among promotion-eligible clubs and third overall.
Tulevik terminated their affiliation with Flora and continued as an independent club in the II Liiga.
Each team played every opponent four times, twice at home and twice away, for a total of 36 games.