The 2011 São Léo Open was a professional tennis tournament played on clay courts.

It was the first edition of the tournament which is part of the 2011 ATP Challenger Tour.

It took place in São Leopoldo, Brazil between 31 October and 6 November 2011.

The following players received wildcards into the singles main draw: The following players received entry as a special exempt into the singles main draw: The following players received entry as an alternate into the singles main draw: The following players received entry from the qualifying draw: Leonardo Mayer def.

Nikola Ćirić, 7–5, 7–6(7–1) Franco Ferreiro / Rubén Ramírez Hidalgo def.