The Itaipava São Paulo Indy 300 presented by Nestlé was the fourth race of the 2011 IZOD IndyCar Series season.

The race took place on May 1 and 2, on the 2.536-mile (4.081 km) temporary street circuit in São Paulo, Brazil, and was telecasted by Versus in the United States and TV Bandeirantes in Brazil.

After a rain delay that lasted almost two and a half hours, attempts to run the event in full on the Sunday were scrapped with the race completed on Monday May 2.

NOTE: Under agreement from race organisers, INDYCAR, and Brazilian television rights holder Rede Bandeirantes, there is a two-hour time limit for this race.

The first 14 laps from Sunday took 40:46 to run, and that time was deducted from Monday morning's race.