The 2011 S.League was the 16th season of the S.League, the top professional football league in Singapore.

As in the previous season the S.League was not allowed to send a team to the AFC Champions League because of the participation of a foreign team in the league.

[1] Beijing Guoan Talent withdrew their participation in the league after just one season.

[2] They were replaced by Tanjong Pagar United, who returned to the highest football league of Singapore after a seven-year absence.

In further changes, Sengkang Punggol were renamed to Hougang United.