The 2011 West Texas A&M Buffaloes football team represented West Texas A&M University during the 2010 NCAA Division II football season as a member of the Lone Star Conference (LSC).

Led by seventh-year head coach Don Carthel, the Buffaloes played their home games at Kimbrough Memorial Stadium in Canyon, Texas.

For just the second time under Carthel, the Buffs failed to receive a bid for the NCAA Division II Playoffs.

Instead, the team was invited to the Kanza Bowl, where they defeated Central Missouri 26–7.

[1] In January 2011, offensive coordinator and quarterbacks coach Mike Nesbitt was hired for the same position with the Stephen F. Austin Lumberjacks.