The 2012–13 DePaul Blue Demons men's basketball team represented DePaul University during the 2012–13 NCAA Division I men's basketball season.

The Blue Demons, led by third year head coach Oliver Purnell, played their home games at the Allstate Arena, with two home games at McGrath-Phillips Arena, and were members of the Big East Conference.

They lost in the first round of the Big East tournament to Rutgers.

This was DePaul's final season as a member of the original Big East Conference (now known as the American Athletic Conference or The American).

The so-called Catholic 7 schools will join with Butler, Creighton and Xavier to form a new conference that will keep the Big East Conference name but will be an entirely new conference.