Regular season started in October 2012 and finished in late April.
After completing 22 matchdays, top team is promoted to Liga ASOBAL, and teams qualified 2nd, 3rd, 4th and 5th play the promotion playoff.
As the champion team was FC Barcelona B, a reserve team, therefore unable to promote, Juanfersa Gijón was automatically promoted.
Ángel Ximénez will play in Liga ASOBAL 2013–14 by winning the promotion playoffs after defeating host team Bidasoa Irún in the final 26–28.
Teams promoted to Liga ASOBAL 2013–14 Teams relegated to 2013–14 Primera Nacional Winner of Final will be promoted to Liga ASOBAL for 2013–14 season.