The winner of this competition earned a place at the group stage of the next season's EuroLeague.

In this edition, semifinals were played in home-and-away series, and the final in a single game.

Valencia BC Unics Kazan ČEZ Basketball Nymburk Uxúe Bilbao Basket Galatasaray Medical Park Cajasol Sevilla Le Mans Sarthe Basket BC Spartak Saint Petersburg Hapoel Jerusalem Lokomotiv Kuban Krasnodar BC Triumph Lyubertsy Panionios BC Cibona Zagreb Banco di Sardegna Sassari Banvit BK Bandırma KK Budućnost VEF Rīga Cholet Basket Belgacom Spirou BC Donetsk Budivelnyk Kyiv Telenet Oostende Azovmash Mariupol Crvena zvezda Orléans Loiret Basket BC Prienai Trefl Sopot Stelmet Zielona Góra Ratiopharm Ulm Artland Dragons s.Oliver Baskets PBC Lukoil Academic The top two teams from each group advanced to the top 16.

If teams were level on record at the end of the Last 16 phase, tiebreakers were applied in the following order: The quarterfinals were two-legged ties determined on aggregate score.

The group winner in each tie, listed as "Team #1", hosted the second leg.