[4] The labels in the parentheses show how each team qualified for the place of its starting round (TH: Euroleague title holders): The qualifying rounds were played in a knock-out tournament consisting of eight teams in a single-venue tournament format.

The qualifying rounds were played between 25 and 28 September at the PalaDesio in Desio, Italy.

FC Barcelona Regal Olympiacos Maccabi Electra Panathinaikos Montepaschi Siena Real Madrid CSKA Moscow Caja Laboral Khimki Partizan Alba Berlin Anadolu Efes Unicaja Málaga Lietuvos Rytas Žalgiris Fenerbahçe Ülker Asseco Prokom EA7 Milano Brose Bamberg Union Olimpija Cedevita Beşiktaş Élan Chalon Mapooro Cantù (q) The regular season began on 11 October 2012.

If teams were level on record at the end of the Regular Season, tiebreakers were applied in the following order: The Top 16 began on 27 December 2012.

If teams were level on record at the end of the Top 16, tiebreakers were applied in the following order: On 12 May 2012 it was announced the Final Four would be hosted at The O2 Arena in London, United Kingdom.