The season was divided into two tournaments (Apertura and Clausura) and determined the 61st and 62nd national champions.
[4][5] On rounds 2 and 3, Vida included midfielder Luis Jaramillo on their lineups despite being ineligible to play; on 12 September, the Northern Disciplinary Commission made the decision to award both matches to Real España and Victoria 3–0.
[6] On 28 October, Club Deportivo Olimpia became the first team to secure a spot for the postseason, after defeating Platense F.C.
The semifinal encounters were settled on 21 November, as Motagua and Atlético Choloma defeated Real España and Marathón respectively.
[9] Once in the semifinals, Olimpia got rid of Atlético Choloma with a 2–1 aggregate, meanwhile Victoria and Motagua finished with a 3–3 global score, however, Victoria advanced thanks to a better regular season finish over Motagua.
With their success in the semifinals, Olimpia and Victoria re-encountered each other in a final for the third time in history,[10] having won one each in the previous two.
The first match in La Ceiba ended with a scoreless tie; but in the second leg, Olimpia had no mercy over Victoria and won its third consecutive title with an overwhelming 4–0.
On 20 April 2013, Atlético Choloma was relegated to the Liga de Ascenso after reaching 38 points, two less than C.D.S.