The 2012–13 season in Primera División de Nicaragua was divided into two tournaments (Apertura and Clausura) and determined the 61st and 62nd champions in the history of the league.

It also provided the country's sole berth for the 2013–14 CONCACAF Champions League.

Promoted from Segunda División de Fútbol Nicaragua.

Chinandega Diriangén FC Juventus Managua Managua (player released mid season) Ocotal Real Esteli Xilotepelt Walter Ferretti

Chinandega Diriangén FC Juventus Managua Managua (player released mid season) Ocotal Real Esteli Xilotepelt Walter Ferretti