San Luis began their season on July 21, 2012 against Santos Laguna, San Luis played most of their homes games on Saturdays at 9:00pm local time.

San Luis did not qualify to the final phase in either the Apertura or Clausura tournament.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Source: Apertura 2012 results Win Draw Loss [18] Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Win Draw Loss San Luis did not qualify to the Final Phase [35] Last updated: 5 May 2013.