In 2012–13 the club played in the Bundesliga, the top tier of German football.

The club also took part in the 2012–13 edition of the DFB-Pokal, where they were eliminated in the first round by fourth division side Berliner AK 07, losing 4–0.

[1] 1899 Hoffenheim began their season with a 4–0 defeat against regional team Berliner AK,[2] the largest victory for a fourth division club against a Bundesliga side.

[3] On 3 December, manager Markus Babbel was released because of poor results, with the team in 16th place in the Bundesliga.

[4][5] Win Draw Loss Postponed 1899 Hoffenheim, as the 16th-placed team, faced third-placed 2012–13 2.