The 2012 6 Hours of São Paulo was held at Autódromo José Carlos Pace, São Paulo on Saturday 15 September 2012, and was the fifth round of the 2012 FIA World Endurance Championship season.

Toyota claimed its first FIA World Endurance Championship victory at the event.

Pole position winners in each class are marked in bold.

Cars failing to complete 70% of winner's distance marked as Not Classified (NC).

50 Larbre Corvette was excluded following the post-race technical checks.