The women's 100 metre breaststroke event at the 11th FINA World Swimming Championships (25m) took place 14 – 15 December 2012 at the Sinan Erdem Dome.

Prior to this competition, the existing world and championship records were as follows.

The following records were established during the competition: [1] [3] [4] The final was held at 19:00.

[5]