The 2012 James Madison Dukes football team represented James Madison University in the 2012 NCAA Division I FCS football season.

They were led by 14th year head coach Mickey Matthews and played their home games at Bridgeforth Stadium and Zane Showker Field.

They are a member of the Colonial Athletic Association.

They finished the season 7–4, 5–3 in CAA play to finish in sixth place.