Purdue will be forced to replace captains Offensive tackle Dennis Kelly, linebacker Chris Carlino, as well as starters Defensive end Gerald Gooden Jr., Linebacker Joe Holland, Safety Albert Evans, Safety Logan Link Offensive tackle Nick Mondek, Kicker Carson Wiggs and Wide receiver Justin Siller, and key contributor Fullback Jared Crank.

The most significant was Running back Reggie Pegram decided to transfer from the program following the bowl game.

[4] Other's that left the program were running backs Doug Gentry[5] and Devin Hill, kicker Ryan Ullrich and defensive tackle LaSalle Cooks.

[8] and Allen as well as Short have both been named to the Chuck Bednarik Award, which is given to the top defensive player in the NCAA.

[13] Following its game against Notre Dame, Purdue returned home to face the Eastern Michigan Eagles of the Mid-American Conference.

[12][14] Following its game against Eastern Michigan, Purdue stayed home to face the Marshall Thundering Herd of Conference USA.

[15] After its game against Michigan, Purdue hosted the Wisconsin Badgers to open up Leaders Division play.

[21] After its game against Illinois, Purdue returned home to play the Indiana Hoosiers in the "Battle for the Old Oaken Bucket".