The 2012 Three Days of De Panne (Dutch: KBC Driedaagse van De Panne-Koksijde 2012) is the 36th edition of the Three Days of De Panne, an annual bicycle race.

Taking part in and around the De Panne region of West Flanders, it began in Middelkerke on 27 March and will finish in De Panne two days later.

It is part of the 2012 UCI Europe Tour and is rated as a 2.HC event.

24 teams were invited to participate in the tour: 10 UCI ProTeams and 14 UCI Professional Continental Teams.

[1] 27 March 2011 – Middelkerke to Oudenaarde, 201.6 km (125.3 mi) 28 March 2012 – Zottegem to Koksijde, 216.1 km (134.3 mi) 29 March 2012 – De Panne to De Panne, 112.1 km (69.7 mi) 29 March 2012 – De Panne to Koksijde to De Panne, 14.7 km (9.1 mi) individual time trial (ITT)