Having won the Gambrinus liga the previous season, they entered the competition as defending champions and finished second.

From the beginning of July the team moved to Austrian Westendorf for a training preparation camp including three games with ex-Bundesliga side Fürth, Russian Premier League team Krasnodar and last year's Champions League participant CFR Cluj.

During the summer transfer window Viktoria introduced two new players – Tomáš Hořava from Olomouc and Milan Petržela, who returned to the club after an unsuccessful season in Augsburg.

EU = if holds or not a European Union passport; Country: when 2 flags, 1st flag = country that plays for internationally, 2nd flag = country of birth; N = number on jersey; P = Position (for position name, pause mouse pointer on abbreviation); Name = Name on jersey (for more extensive name, pause mouse pointer on name); Age = age on the day of the signing; Moving from = only indicate the club the player was playing before start playing for this club in this season, for the type of the moving see Status column; Moving to = only indicates the club the player is going to play next, for the type of the moving see Status column; Ends = when the player's current contract ends; n/a = Not applicable.

Plzeň's manager Pavel Vrba left many key players on the bench before the first leg of the second qualifying round of Champions League, which was four days later.