Appearing in this round were bottom 9 teams from 2012–13 Serbian First League, as well as 5 regional cup winners.
Bottom 9 teams from 2012–13 Serbian First League (Sloga Kraljevo, Timok, Inđija, Teleoptik, Radnički Nova Pazova, Banat Zrenjanin, OFK Mladenovac, Kolubara and RFK Novi Sad) were set as seeded teams, with 5 regional cup winners (IM Rakovica, Partizan Bumbarevo Brdo, Trstenik PPT, Radnički Sremska Mitrovica and Mokra Gora) being set as unseeded teams.
Thus only 15 teams from 2012–13 Serbian SuperLiga (Partizan, Crvena zvezda, Vojvodina, Jagodina, Sloboda Užice, OFK Beograd, Rad, Spartak Subotica, Javor Ivanica, Donji Srem, Radnički Niš, Radnički 1923, Novi Pazar, BSK Borča (II), Smederevo (II)) were set as seeded teams.
After 15 drawn ties, remaining undrawn unseeded team was Voždovac, and it received an automatic bye to the next round.
No extra time was played if the score was tied after regular 90 minutes, with games going straight into penalties.
Seeded teams: Partizan, Crvena Zvezda, Vojvodina, Jagodina, Sloboda Užice, OFK Beograd, Spartak Subotica and Donji Srem.
Unseeded teams: Crvena Zvezda, Sloboda Užice, Spartak Subotica, Donji Srem.
4 winners from Quarter finals (Jagodina, Vojvodina, OFK Beograd and Spartak Subotica) take part in this stage of the competition.