The knock-out stage of the 2013 AFC Champions League was played from 14 May to 9 November 2013.
A total of 16 teams competed in the knock-out stage.
In the knock-out stage, the 16 teams played a single-elimination tournament.
Each tie was played on a home-and-away two-legged basis.
The away goals rule, extra time (away goals do not apply in extra time) and penalty shoot-out were used to decide the winner if necessary.
The draw for the quarter-finals, semi-finals, and final (to decide the order of two legs) was held on 20 June 2013, 16:00 UTC+8, at the AFC House in Kuala Lumpur, Malaysia.