The winner of the event earns the league's automatic bid to the 2013 NCAA Division I baseball tournament.
TCU and West Virginia, new members of the league, are eligible for their first tournaments.
Iowa State discontinued their program after the 2001 season without having won a title.
Fourth-seeded Oklahoma defeated sixth-seeded Kansas in the championship game to claim their second Big 12 Baseball Conference Tournament title.
Due to the 2013 Moore tornado, just outside the Oklahoma City site of the Tournament, the Big 12 announced a delay in the start of the event and a change in format from the planned double-elimination tournament.