The 2013 Grand Prix Cycliste de Québec was the fourth edition of the Grand Prix Cycliste de Québec, a single-day professional bicycle road race.

It was held on 13 September 2013, over a distance of 201.6 km (125.3 mi), starting and finishing in Quebec City.

The race is one of the only two events which are part of the World Tour calendar in North America, the other one being the 2013 Grand Prix Cycliste de Montréal contested two days later.

As the Grand Prix Cycliste de Québec was a UCI World Tour event, all 19 UCI ProTeams were invited automatically and obligated to send a squad.

A Canadian national squad also competed in the race, and as such, formed the event's 21-team peloton.