The Galaxy entered the season as the two-time defending MLS Cup champions.
They were eliminated by Real Salt Lake in the Conference Semifinals of the MLS Cup Playoffs.
The team reached the semifinals of the 2012–13 CONCACAF Champions League, where they were knocked out by Monterrey.
The Galaxy also qualified for the 2013–14 CONCACAF Champions League by virtue of winning the 2012 MLS Cup.
Note: Flags indicate national team as defined under FIFA eligibility rules.