Michigan went on to lose five of their final six games, eventually dropping out of the AP poll, ending with a loss to Kansas State in the 2013 Buffalo Wild Wings Bowl.

[1] The 2012 team compiled an 8–5 record under second-year head coach Brady Hoke and faced South Carolina in the Outback Bowl, losing 33–28 on a last-minute touchdown.

On March 20, the team announced that returning starting linebacker Jake Ryan suffered a torn ACL and was listed as out indefinitely.

Floyd, center Elliott Mealer, offensive guards Patrick Omameh and Ricky Barnum, tight end Mike Kwiatkowski, and wide receiver Roy Roundtree.

Fitzgerald Toussaint rushed one-yard for a touchdown before Coluzzi added another field goal for Central Michigan, this time from a distance of 27 yards.

[36] Backup running back Drake Johnson suffered a torn ACL during the game and will miss the remainder of the season.

[42] Michigan opened the scoring in the first quarter with a 44-yard field goal from Brendan Gibbons and added a 61-yard touchdown pass from Devin Gardner to Jeremy Gallon to expand its lead to 10–0.

Notre Dame answered with a seven-yard touchdown pass from Tommy Rees to T. J. Jones, making the score at the end of the first quarter 10–7 in favor of Michigan.

Notre Dame tied the game in the second quarter with a 44-yard field goal from Kyle Brindza, but Michinga regained the via a two-yard touchdown run from Devin Gardner.

The only two Michigan players to contribute more total yards in a single game are Denard Robinson and John Navarre.

Gallon's 184 receiving yards against Notre Dame is tied for the sixth highest single-game performance in Michigan history.

Stephen M. Ross, who donated $200 million to the University of Michigan earlier in the week, was named an honorary captain for the game.

[58] Michigan won its second close game in two weeks, scoring 17 unanswered points to defeat UConn 24–21 after falling behind 21–7 in the third quarter.

Michigan's defense only allowed 206 yards of total offense and held UConn to one successful third down conversion out of eleven attempts.

Michigan scored the first points of the third quarter on a two-yard touchdown run from Derrick Green, but Minnesota responded with a 44-yard field goal from Chris Hawthorne.

Penn State responded with a 45-yard field goal from Sam Ficken, but Michigan regained the lead via a 16-yard touchdown pass from Gardner to Jeremy Gallon.

Penn State scored the next ten points—a 43-yard field goal from Ficken and a one-yard run from Hackenberg—to tie the game and send it to overtime.

Indiana answered with a five-yard touchdown pass from Roberson to Wynn and then reduced Michigan's lead to one point with a 23-yard field goal from Ewald.

[76] Jeremy Gallon broke the single-game receiving record for both Michigan and the Big Ten Conference during the game, catching 14 passes for a total of 369 yards.

The previous meeting saw Michigan lose starting quarterback Denard Robinson to injury in the first half and it eventually lost the game 23–9.

[85] Nebraska opened the scoring in the first quarter via a 21-yard field goal from Pat Smith and an eight-yard run from Ameer Abdullah.

Michigan responded in the second quarter with a 27-yard field goal from Brendan Gibbons, giving Nebraska a 10–3 lead at halftime.

[88] Michigan stunned Northwestern with a last second field goal to tie the game, and then won in triple overtime by a score of 27–19.

Jeremy Gallon became the school's tenth player to record 1,000 receiving yards in a season and the first since Mario Manningham did so in 2007.

In the third quarter, Jake Rudock completed a 55-yard touchdown pass to Tevaun Smith, cutting Michigan's lead to seven points.

In the fourth quarter, Mark Weisman tied the game via a nine-yard touchdown run, and Mike Myer gave Iowa the victory with a 34-yard field goal.

[98] Ohio State won a thrilling contest 42–41 after Michigan missed a go-ahead two-point conversion attempt with 32 seconds remaining in the game.

[101] For its final game of the season, Michigan faced Kansas State in the Buffalo Wild Wings Bowl.

The radio announcers were Frank Beckmann with play-by-play, Jim Brandstatter with color commentary, and Doug Karsch with sideline reports.

[118] In addition to the drafted players both Thomas Gordon (New York Giants) and Fitzgerald Toussaint (Baltimore Ravens) signed contracts as undrafted free agents.