The regular season began at home with a loss against the Chicago Cubs on April 1 and ended with a win at Great American Ball Park against the Cincinnati Reds on September 29.

In doing so, the team advanced to the NLDS, where they were defeated in five games by the eventual National League champion Cardinals, eliminating them from the 2013 postseason.

Five members of the 2013 Pirates were selected to represent the National League in the All-Star Game.

In addition, team manager Clint Hurdle won the 2013 NL Manager of the Year Award in his third year with the Pirates, center fielder Andrew McCutchen was named NL Most Valuable Player, pitcher Francisco Liriano was named NL Comeback Player of the Year, and third baseman Pedro Álvarez tied for first place in home runs hit in the National League at 36.

Infielders Outfielders Manager Coaches 2013 Major League Baseball All-Star Game[10] NL Player of the Week MLB Delivery Man of the Month Award NL Rookie of the Month The Sporting News Comeback Player of the Year Award The Sporting News Manager of the Year Award NL Comeback Player of the Year NL Manager of the Year