Andretti Autosport driver Matthew Brabham won the championship with two races remaining capturing a series-record 11th win in his rookie season.
Brabham's Andretti Autosport teammate Shelby Blackstock won a single race and two poles and finished third in points.
Team Pelfrey's Spencer Pigot also won a single race and finished fourth in points.
Andretti Autosport also captured the team championship with two races remaining, their first in Pro Mazda.
American Jay Horak won the championship with eight race starts by a narrow margin over Bobby Eberle, who also completed a partial schedule.