The tournament was played on a knockout format, originally a total of 51 teams were to participate, due to withdraws a total of 49 teams participated.

Initially 35 teams were allocated vacancies to enter the competition at the 'Qualification phase', with another 14 teams (after 2 teams withdraw) joining from the Women's CEV Cup entering the competition at the 'Main phase' stage (as per 'Round composition' below).

After two legs, the team with the most result points advanced to the next round.

[3][4] In this stage of the competition, the sixteen qualified teams of the Qualification phase were joined by the losing teams from the 2014–15 Women's CEV Cup.

Bursa BBSK ŽOK Bimal-Jedinstvo Brčko Linamar Békéscsabai RSE Jedinstvo Stara Pazova Schweriner SC Asterix Kieldrecht Alterno Apeldoorn ASPTT Mulhouse Azerrail Baku Stod Volley Steinkjer TSV Düdingen Kanti Schaffhausen Hapoel Kfar Saba AON Pannaxiakos Naxos İlbank Ankara Uralochka-NTMK Ekaterinburg Rocheville Le Cannet VDK Gent Dames Dinamo Romprest București Volley Köniz Haifa VC ASKÖ Linz-Steg Orbita ZTMC-ZNU Zaporozhye Khimik Yuzhny Sagres Neuchâtel UC SK UP Olomouc Rote Raben Vilsbiburg Calcit Kamnik ATSC Sparkasse Klagenfurt Igor Gorgonzola Novara