The 2014–15 season was Unione Calcio Sampdoria's third season back in Serie A after having been relegated at the end of the 2011–12 season.

The team competed in Serie A, finishing seventh and qualifying for the 2015–16 UEFA Europa League, and the Coppa Italia, finishing in the Round of 16.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Players may hold more than one non-FIFA nationality.

Source: Competitive matches Last updated: 31 May 2015Source: Competitions