Atlético El Vigía and Yaracuyanos were relegated after accumulating the fewest points in the 2013–14 season aggregate table.
They will be replaced by Metropolitanos and Portuguesa, the 2013–14 Segunda División winner and runner-up, respectively.
Deportivo Táchira and Trujillanos qualified to the Serie Final, which was contested on a home and away basis.
Other than the teams which already qualify for the Copa Libertadores (Apertura and Clausura champions and the best-placed team in the aggregate table) and the Copa Sudamericana (Copa Venezuela champion and the second best-placed team in the aggregate table), the eight best-placed teams in the aggregate table will contest in the Serie Sudamericana for the remaining two berths to the Copa Sudamericana, which qualify the two winners to the First Stage.
In the first round, the matchups are: In the second round, the matchups are: For the two second round winners, the team with the better record in the aggregate table will receive the Venezuela 3 berth, while the other team will receive the Venezuela 4 berth.